Photodynamic Therapy Authors:
نویسنده
چکیده
Rufino Silva, MD, PhD Centro Hospitalar e Universitário de Coimbra (CHUC). Coimbra, Portugal Faculty of Medicine, University of Coimbra. Portugal (FMUC) Association for Innovation and Biomedical Research on Light and Image (AIBILI). Coimbra. Portugal Introduction Photodynamic therapy was approved in 2000 as an alternative treatment for patients with AMD of the exudative form, having been the first effective pharmacological treatment for this form of the disease. Until then, laser photocoagulation was only successful in treating a small percentage of neovascular lesions (juxtafoveal and extrafoveal), excluding subfoveal lesions, which are more frequent. With the emergence of antiangiogenic therapies, photodynamic therapy has been used less frequently. However, it remains useful in three situations: in patients with systemic or ocular contraindications regarding intravitreal administration of antiangiogenic drugs, as an adjuvant, in combination with other drugs, and in the treatment of polypoidal choroidal vasculopathy and central serous chorioretinopathy.
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